Sex-specific differences in infranodal conduction properties in patients undergoing transcatheter aortic valve replacement

Abstract Funding Acknowledgements Type of funding sources: None. Background Electrophysiological (EP) testing has been proposed for risk stratification patients with left bundle branch block (LBBB) after transcatheter aortic valve replacement (TAVR). A uniform cut-off 70ms the His-Ventricular (HV) interval to trigger pacemaker implantation. However, sex-specific periprocedural data regarding infranodal conduction properties are lacking. Purpose We aimed compare HV in men and women undergoing TAVR. Methods analyzed consecutive prospectively included TAVR between June 2020 2021 at a tertiary referral center. EP was performed all pre- post-valve deployment case LBBB additionally third time following day. Results 127 were (81 ± 7 years, 46% female). Median pre-valve 43 [37-50] ms vs 46 [42-53] men, respectively (p=0.016). Nine underwent peri-procedural (PM) implantation third-degree AV-block. The median 54 [42-59] 56 [51-61] (p=0.038). day 45 [41-49] 50 [48-62] (p=0.048). An ≥ 55 ≥70 present seven (24%, two females) three (10%, one (Figure) Conclusion Women have shorter intervals pre-and post-valve-deployment as well compared men. Further studies evaluating cut-offs warranted.